There is generally poor recovery of these functions because of the difficulty of tissue regeneration in the central nervous system. In spinal cord injury (SCI), complete or partial loss of autonomic, sensory, and motor functions is caused by interruption of neural signal conduction along the axonal tracts. Spinal cord injury (SCI), a devastating condition affecting the central nervous system, is associated with sensory, motor and visceral function impairment as well as chronic pain Keywords: Nerve, Nucleo CMP Forte, rats, regeneration.Ībbreviations: SCI: Spinal cord injury CMP: cytosine monophosphate. In Nucleo CMP Forte the results showed that the improvement of motor and sensory functions, degree of spinal cord cooptation and the glial scar formation and axonal regeneration were less than that Nucleo CMP Forte, this being more obvious in respect to the macroscopic findings in which the degree of spinal cord cooptation was better than the other group, microscopic findings also showed massive glial scar formation and axonal regeneration in the same group. Results indicate that the axonal regeneration. Animals of each group sacrificed on two periods of time after 6, 12 weeks, clinical assessment for the motor and sensory functions were done throughout the time of experiment, macroscopic and microscopic examination of the spinal cord were done after sacrificing of the animals. In the group of Nucleo CMP, The group of which administered CMP. Nucleo CMP Forte (30 mg/kg) was given intramuscularly in Nucleo CMP immediately after spinal cord transection in CMP treated group. Twenty adult white rats were used in this study, divided into two groups, each group consists of ten animals control group and Nucleo CMP forte treated group Spinal cord had been transected in all animals of experiment control group and. This study was carried out to evaluate the efficacy of Nucleo CMP Forte therapy as a single therapy on the regeneration of spinal cord injury in laboratory rats.

Cmp nucleo forte